A clinical trial is conducted to compare an experimental medication

     A clinical   trial is conducted to compare an experimental medication to placebo to reduce   the symptoms of asthma. Two hundred participants are enrolled in the study   and randomized to receive either the experimental medication or placebo. The   primary outcome is self-reported reduction of symptoms. Among 100   participants who received the experimental medication, 38 reported a   reduction of symptoms as compared to 21 participants of 100 assigned to   placebo. Test if there is a significant difference in the proportions of   participants reporting a reduction of symptoms between the experimental and   placebo groups. Use a 5% level of significance. Run the test using the   five-step approach. In computing this, fully discuss: The five step approach.    

 
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